HORMAD2 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD253135A
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using HORMAD2 Polyclonal Antibody at dilution of 1:35(×200)
Immunohistochemistry of paraffin-embedded Human prost ate cancer tissue using HORMAD2 Polyclonal Antibody at dilution of 1:35(×200)
Variation
Quantity
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Overview
Product Name
HORMAD2 Polyclonal Antibody
Catalog Number
RD253135A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
Essential for synapsis surveillance during meiotic prophase via the recruitment of ATR activity. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process believed to form the basis of meiotic silencing of unsynapsed chromatin (MSUC) and meiotic prophase quality control in both sexes. Required for the DNA double-strand break-independent, BRCA1-dependent activation of ATR on the sex chromosomes that is essential for normal sex body formation (By similarity).
Immunogen Information
Immunogen
Fusion protein of human HORMAD2
Swissprot
Q8N7B1
Synonyms
4930529M09RikCT46.2HORM2HORMA domain containing 2HORMA domain-containing protein 2Hormad2MGC26710RP23-329P17.4
Gene Accession
BC030013
Applications
Reactivity
Human
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:100, ELISA 1:5000-1:10000
Concentration
0.96 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas