HSD17B12 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD78158A
Western Blot analysis of A172 and A375 cell using HSD17B12 Polyclonal Antibody at dilution of 1:650
Immunohistochemistry of paraffin-embedded Human liver cancer using HSD17B12 Polyclonal Antibody at dilution of 1:40
Product Name
HSD17B12 Polyclonal Antibody
Catalog Number
RD78158A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes a very important 17beta-hydroxysteroid dehydrogenase (17beta-HSD) that converts estrone into estradiol in ovarian tissue. This enzyme is also involved in fatty acid elongation. Catalyzes the transformation of estrone (E1) into estradiol (E2), suggesting a central role in estrogen formation. Its strong expression in ovary and mammary gland suggest that it may constitute the major enzyme responsible for the conversion of E1 to E2 in women.
Immunogen Information
Immunogen
Recombinant protein of human HSD17B12
Swissprot
Q53GQ0
Synonyms
123-ketoacyl-CoA reductaseshort chain17 beta HSD 1217 beta hydroxysteroid dehydrogenase 1217-@beta-HSD XII17-@beta-hydroxysteroid dehydrogenase XII17-beta-HSD 1217-beta-hydroxysteroid dehydrogenase 1217beta HSD type 123 ketoacyl CoA reductase3-
Calculated MW
34 kDa
Gene Accession
BC012043
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:50-1:200
Concentration
0.3 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas