HSD17B2 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD75894A
Western Blot analysis of Human fetal liver tissue using HSD17B2 Polyclonal Antibody at dilution of 1:300
Immunohistochemistry of paraffin-embedded Human esophagus cancer using HSD17B2 Polyclonal Antibody at dilution of 1:50
Immunohistochemistry of paraffin-embedded Human brain using HSD17B2 Polyclonal Antibody at dilution of 1:50
Product Name
HSD17B2 Polyclonal Antibody
Catalog Number
RD75894A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
17β-HSD2 (17β hydroxysteroid dehydrogenase type 2) belongs to the 17β-HSD family of proteins that regulate the availability of steroids within a tissue. 17β-HSD2 converts active steroids to their inactive form through its oxidative activity. It is a key player in the inactivation of Estradiol and testosterone. Due to the affects that 17β-HSD2 has on the availability of estrogen, it has been extensively investigated for playing a possible role in breast tumor development, colon cancer development and the pathophysiology of endometriosis.
Immunogen Information
Immunogen
Recombinant protein of human HSD17B2
Swissprot
P37059
Synonyms
17 beta HSD 217-beta-HSD 217-beta-hydroxysteroid dehydrogenase type 220 alpha HSD20 alpha hydroxysteroid dehydrogenase20 alpha-hydroxysteroid dehydrogenase20-alpha-HSDDHB2E2DHEDH17B2Estradiol 17-beta-dehydrogenase 2HSD17Hsd17b2Hydroxysteroid
Calculated MW
43 kDa
Gene Accession
BC009581
Applications
Reactivity
Human
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:50-1:200
Concentration
0.5 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas