HSP90 alpha Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD70348A
Western Blot analysis of various samples using HSP90 alpha Polyclonal Antibody at dilution of 1:1000.
Product Name
HSP90 alpha Polyclonal Antibody
Catalog Number
RD70348A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
HSP90,encoded by HSP90AA1,is a constitutively and ubiquitously expressed molecular chaperone that is crucial for the stability and function of many proteins. HSP90 provides chaperoning activity for client proteins; many of them are members of oncogenic pathways,indicating its implication in tumor malignancy. HSP90 mainly resides in the cytosol,while it can also be released to the extracellular space. Secreted Hsp90 is a C-terminal truncated form. It has been reported that the level of plasma Hsp90 is positively correlated with tumor malignancy in clinical cancer patients,and can be a promising diagnostic marker for tumor malignancy in clinical application.
Immunogen Information
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse HSP90A
Swissprot
P07900,P82995,P07901
Synonyms
EL52epididymis luminal secretory protein 52Heat shock 86 kDaheat shock 90kD protein 1alphaHeat shock 90kD protein 1alpha like 4heat shock 90kD proteinalpha-like 4Heat shock 90kDa protein 1 alphaHeat shock protein 90kDa alpha (cytosolic) class A
Calculated MW
90 kDa
Observed MW
90 kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
460 μg/mL
Storage Buffer
PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas