This intronless gene encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins.
Immunogen Information
Immunogen
Recombinant protein corresponding to Mouse HSP70
Swissprot
P0DMV8,Q61696,P0DMW0
Synonyms
heat shock protein family A (Hsp70) member 1Aheat shock protein family A (Hsp70) member 1BHSP70-1BHSP70-2HSP70.2
Calculated MW
70 kDa
Observed MW
70 kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:300-1:800
Concentration
2 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4