G-protein coupled receptor for 5-hydroxytryptamine (serotonin. Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.
Immunogen Information
Immunogen
Recombinant fusion protein of human HTR1F
Gene ID
3355
Swissprot
P30939
Synonyms
HTR1F5-HT-1F5-HT1F5HT6HTR1ELMR77
Calculated MW
43kDa
Observed MW
38kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1mg/mL
Storage Buffer
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.