The protein encoded by this gene localizes to the mitochondrion and is part of the iron-sulfur cluster assembly pathway. The encoded protein functions late in the biosynthesis of mitochondrial 4Fe-4S proteins. Defects in this gene have been associated with autosomal recessive spastic paraplegia-74 and with multiple mitochondrial dysfunctions syndrome-3. Two transcript variants encoding different isoforms have been found for this gene. The smaller isoform is not likely to be localized to the mitochondrion since it lacks the amino-terminal transit peptide.
Immunogen Information
Immunogen
Synthetic peptide of human IBA57
Swissprot
Q5T440
Synonyms
C1orf69CAF17Chromosome 1 open reading frame 69FLJ12734FLJ13849IBA57IBA57 homolog iron sulfur cluster assemblyIBA57 iron sulfur cluster assembly homologIBA57 iron sulfur cluster assembly homolog (S. cerevisiae)IBA57S. cerevisiaehomolog ofIro
Gene Accession
NP001010867
Applications
Reactivity
Human
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:30-1:150, ELISA 1:5000-1:10000
Concentration
0.9 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
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