IBSP Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD252125A
Western blot analysis of Human fetal liver tissue lysate using IBSP Polyclonal Antibody at dilution of 1:650
Product Name
IBSP Polyclonal Antibody
Catalog Number
RD252125A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
The protein encoded by this gene is a major structural protein of the bone matrix. It constitutes approximately 12% of the noncollagenous proteins in human bone and is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and osteoclasts. The only extraskeletal site of its synthesis is the trophoblast. This protein binds to calcium and hydroxyapatite via its acidic amino acid clusters, and mediates cell attachment through an RGD sequence that recognizes the vitronectin receptor.
Immunogen Information
Immunogen
Synthetic peptide of human IBSP
Swissprot
P21815
Synonyms
BNSPBone sialoprotein 2Bone sialoprotein IIBSPBSP IIBSPIICell binding sialoproteinCell-binding sialoproteinIBSPIntegrin binding sialoproteinIntegrin-binding sialoproteinSIALSPII
Calculated MW
35 kDa
Observed MW
Refer to figures
Gene Accession
NP004958
Applications
Reactivity
Human, Mouse
Tested Applications
WB,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, ELISA 1:5000-1:10000
Concentration
0.78 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas