IBSP Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD266728A
Western blot analysis of extracts of various cell lines using IBSP Polyclonal Antibody at dilution of 1:1000.
Product Name
IBSP Polyclonal Antibody
Catalog Number
RD266728A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The protein encoded by this gene is a major structural protein of the bone matrix. It constitutes approximately 12% of the noncollagenous proteins in human bone and is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and osteoclasts. The only extraskeletal site of its synthesis is the trophoblast. This protein binds to calcium and hydroxyapatite via its acidic amino acid clusters, and mediates cell attachment through an RGD sequence that recognizes the vitronectin receptor.
Immunogen Information
Immunogen
A synthetic peptide of human IBSP (NP_004958.2).
Gene ID
3381
Swissprot
P21815
Synonyms
IBSPBNSPBSPBSP-IISP-II
Calculated MW
35 kDa
Observed MW
45 kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas