Icam5 Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD266553A
Western blot analysis of extracts of Mouse brain using Icam5 Polyclonal Antibody at dilution of 1:1000.
Western blot analysis of extracts of Mouse brain using Icam5 Polyclonal Antibody at dilution of 1:1000.
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Overview

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Product Name
Icam5 Polyclonal Antibody
Catalog Number
RD266553A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit

Background

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ICAM-5, also known as telencephalin, is a type I integral membrane glycoprotein of the immunoglobulin superfamily. It is specifically expressed in the postnatal excitatory neuronal cell bodies, dendritic shafts, and dendritic filopodia of the telencephalon. ICAM-5 functions in both the immune and nervous systems. ICAM-5 strongly stimulates neurite outgrowth. It is cleaved by matrix metalloproteases upon activation of glutamate receptors or degraded through endocytosis resulting in increased spine maturation. The cleaved soluble fragment of ICAM-5 is immunosuppressive, which may be important in neuronal inflammatory diseases.

Immunogen Information

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Immunogen
Recombinant fusion protein of mouse Icam5 (NP_032345.2).
Gene ID
15898
Swissprot
Q60625
Synonyms
ICAM5TLCNTLNIcam5
Calculated MW
96 kDa
Observed MW
140 kDa

Applications

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Reactivity
Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

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