IFNAR1 (Interferon Alpha And Beta Receptor Subunit 1) is a Protein Coding gene. Diseases associated with IFNAR1 include Septicemic Plague and Hepatitis C. Among its related pathways are Type I Interferon Signaling Pathways and Immune response IFN alpha/beta signaling pathway. GO annotations related to this gene include interferon receptor activity and type I interferon receptor activity. An important paralog of this gene is ENSG00000249624.The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The encoded protein also functions as an antiviral factor.
Immunogen Information
Immunogen
Recombinant Mouse Ifnar1 protein expressed by E.coli
Swissprot
P33896
Synonyms
Alpha type antiviral proteinAntiviral proteinalpha-typeAntiviral proteinbeta-typeAVPBeta type antiviral proteinCRF2-1Cytokine receptor class-II member 1Cytokine receptor family 2 member 1IFN alpha RECIFN alpha receptorIFN alpha/beta Receptor a
Calculated MW
48kDa
Observed MW
46kDa,54kDa
Applications
Reactivity
Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:1000
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH 7.4
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.