IFT57 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD252949A
Immunohistochemistry of paraffin-embedded Human tonsil tissue using IFT57 Polyclonal Antibody at dilution of 1:85(×200)
Product Name
IFT57 Polyclonal Antibody
Catalog Number
RD252949A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity). Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear.
Immunogen Information
Immunogen
Fusion protein of human IFT57
Swissprot
Q9NWB7
Synonyms
CDNA FLJ10147 fis clone HEMBA1003369Dermal papilla derived protein 8Dermal papilla-derived protein 8DERP 8DERP8Esrrbl 1Esrrbl1ESRRBL1 proteinEstrogen related receptor beta like 1Estrogen related receptor beta like protein 1Estrogen-related recep
Gene Accession
BC011899
Applications
Reactivity
Human, Mouse
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:300, ELISA 1:5000-1:10000
Concentration
1.5 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas