IFT74 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD78978A
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using IFT74 Polyclonal Antibody at dilution 1:60
Immunohistochemistry of paraffin-embedded Human breast cancer tissue using IFT74 Polyclonal Antibody at dilution 1:60
Product Name
IFT74 Polyclonal Antibody
Catalog Number
RD78978A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Capillary morphogenesis protein 1 (CMG1), also known as intraflagellar transport protein 74 (ITP74) or coiled-coil domain-containing protein 2 (CCDC2), is a 600 amino acid human homologue of IFT-71, a complex B protein supporting intraflagellar transport (IFT) in Chlamydomonas. CMG1 localizes to the cytoplasmic vesicle and is highly expressed in adult and fetal kidney and testis, with lower levels of expression in adult heart, placenta, lung, liver and pancreas, and in fetal heart, lung and liver. CMG1 has been suggested to have a role in the primary cilia of HUVEC, and it also functions as a transcriptional regulator of cyclin D2 in spermatocyte-derived cells.
Immunogen Information
Immunogen
Synthetic peptide of human IFT74
Swissprot
Q96LB3
Synonyms
intraflagellar transport 74Chlamydomonashomolog ofCapillary morphogenesis gene 1 proteinCapillary morphogenesis protein 1Ccdc2CMG 1CMG-1Coiled-coil domain containing 2Coiled-coil domain-containing protein 2IFT74IFT74intraflagellar transport 74
Gene Accession
NP_001092692
Applications
Reactivity
Human
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
1.2 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas