This gene encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF-I and IGF-II with relatively low affinity, and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and one variant has been associated with retinal arterial macroaneurysm
Immunogen Information
Immunogen
Synthetic peptide of human IGFBP7
Swissprot
Q16270
Synonyms
AGMAngiomodulinFSTL2IBP-7IBP7IBP7IGF binding protein 7IGF-binding protein 7IGFBP rP1IGFBP-7IGFBP-rP1IGFBP7IGFBPRP1Insulin like growth factor binding protein 7Insulin-like growth factor-binding protein 7MAC25MAC25 proteinPGI2 stimulating f
Calculated MW
29 kDa
Gene Accession
NP_001544
Applications
Reactivity
Human,Mouse
Tested Applications
WB,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
0.3 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4