IL10RA Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD267338A
Immunohistochemistry of paraffin-embedded Rat brain using IL10RA Polyclonal Antibody at dilution of 1:200 (40x lens).
Immunohistochemistry of paraffin-embedded Rat brain using IL10RA Polyclonal Antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded Mouse brain using IL10RA Polyclonal Antibody at dilution of 1:100 (40x lens).
Immunofluorescence analysis of U2OS cells using IL10RA Polyclonal Antibody
Product Name
IL10RA Polyclonal Antibody
Catalog Number
RD267338A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.
Immunogen Information
Immunogen
Recombinant fusion protein of human IL10RA (NP_001549.2).
Gene ID
3587
Swissprot
Q13651
Synonyms
IL10RACD210CD210aCDW210AHIL-10RIL-10R1IL10R
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC,IF
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200 IF 1:50-1:200
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas