IL12A Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD89269A
Western blot analysis of extracts of RAW264.7 cells using IL12A Polyclonal Antibody at 1:1000 dilution.
Western blot analysis of extracts of Recombinant Human IL12A/NKSF1 Protein using IL12A Polyclonal Antibody at 1:1000 dilution.
Product Name
IL12A Polyclonal Antibody
Catalog Number
RD89269A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. This cytokine is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th1 and Th2 cells. The responses of lymphocytes to this cytokine are mediated by the activator of transcription protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity.
Immunogen Information
Immunogen
A synthetic peptide of human IL12A
Gene ID
3592
Swissprot
P29459
Synonyms
P35CLMFNFSKNKSF1IL-12A
Calculated MW
54kDa
Observed MW
55KDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1mg/mL
Storage Buffer
PBS with 0.05% proclin300,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Research Areas