IL2 is a secreted cytokine involved in the operation and regulation of immune system. IL2 plays a pivotal role in T-cell activation and effector functions,including T cell proliferation,interferon-γproduction and cytotoxicity. IL2 can stimulate the propagation of lymphocytes and induce the cytotoxic T lymphocytes and lymphokine-activated killer cells for tumor cells. IL2 also influences memory T cell homeostasis through the regulation of memory T cell numbers and enhances major histocompatibility complex II (MHC II) expression on tumor cells.
Immunogen Information
Immunogen
Recombinant Mouse Interleukin-2 protein
Swissprot
P04351
Synonyms
AldesleukinIL 2IL-2IL2IL2Interleukin 2Interleukin-2Involved in regulation of T cell clonal expansionLymphokineOTTHUMP00000164090POIL2T Cell Growth FactorT-cell growth factorTCGF
Applications
Reactivity
Human,Mouse
Tested Applications
IHC
Conjugation
Unconjugated
Dilution
IHC 1:100-1:200
Concentration
1 mg/mL
Storage Buffer
PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.