IL36A (Interleukin 36, Alpha) is a Protein Coding gene. Diseases associated with IL36A include Psoriasis. Among its related pathways are Innate Immune System and Toll-Like receptor Signaling Pathways. GO annotations related to this gene include cytokine activity and interleukin-1 receptor binding. An important paralog of this gene is IL36G.The protein encoded by this gene is a cytokine that can activate NF-kappa-B and MAPK signaling pathways to generate an inflammatory response. The encoded protein functions primarily in skin and demonstrates increased expression in psoriasis. In addition, decreased expression of this gene has been linked to a poor prognosis in both hepatocellular carcinoma and colorectal cancer patients.
Immunogen Information
Immunogen
Synthetic peptide of human IL36A
Swissprot
Q9UHA7
Synonyms
FIL1FIL1 epsilonFIL1(EPSILON)FIL1EIL 1 epsilonIL 1F6IL 1H1IL-1 epsilonIL-1F6IL1EIL1F6IL1F6IL1RP2IL36AInterleukin 1 epsilonInterleukin 1 family member 6 (epsilon)Interleukin 1 family member 6Interleukin 36 alphaInterleukin-1 epsilonInter