IL36A Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
Western blot analysis of Mouse liver tissue and Human tonsil tissue lysates  using IL36A Polyclonal Antibody at dilution of 1:300
Western blot analysis of Mouse liver tissue and Human tonsil tissue lysates using IL36A Polyclonal Antibody at dilution of 1:300
Immunohistochemistry of paraffin-embedded Human tonsil tissue  using IL36A Polyclonal Antibody at dilution of 1:30(×200)
Immunohistochemistry of paraffin-embedded Human tonsil tissue using IL36A Polyclonal Antibody at dilution of 1:30(×200)
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Overview

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Product Name
IL36A Polyclonal Antibody
Catalog Number
RD218108A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit

Background

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IL36A (Interleukin 36, Alpha) is a Protein Coding gene. Diseases associated with IL36A include Psoriasis. Among its related pathways are Innate Immune System and Toll-Like receptor Signaling Pathways. GO annotations related to this gene include cytokine activity and interleukin-1 receptor binding. An important paralog of this gene is IL36G.The protein encoded by this gene is a cytokine that can activate NF-kappa-B and MAPK signaling pathways to generate an inflammatory response. The encoded protein functions primarily in skin and demonstrates increased expression in psoriasis. In addition, decreased expression of this gene has been linked to a poor prognosis in both hepatocellular carcinoma and colorectal cancer patients.

Immunogen Information

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Immunogen
Synthetic peptide of human IL36A
Swissprot
Q9UHA7
Synonyms
FIL1FIL1 epsilonFIL1(EPSILON)FIL1EIL 1 epsilonIL 1F6IL 1H1IL-1 epsilonIL-1F6IL1EIL1F6IL1F6IL1RP2IL36AInterleukin 1 epsilonInterleukin 1 family member 6 (epsilon)Interleukin 1 family member 6Interleukin 36 alphaInterleukin-1 epsilonInter
Calculated MW
18 kDa
Observed MW
Refer to figures
Gene Accession
NP055255

Applications

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Reactivity
Human, Mouse
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:30-1:150, ELISA 1:5000-1:10000
Concentration
0.78 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

Research Areas

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