IL6R Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD240344A
Western Blot analysis of Rat liver, Mouse spleen and Mouse liver using IL6R Polyclonal Antibody at dilution of 1:2000
Western Blot analysis of Rat spleen using IL6R Polyclonal Antibody at dilution of 1:2000
Western Blot analysis of Jurkat and Hela Cells using IL6R Polyclonal Antibody at dilution of 1:2000
Immunohistochemistry of paraffin-embedded Mouse spleen using IL6R Polyclonal Antibody at dilution of 1:200
Immunohistochemistry of paraffin-embedded Rat spleen using IL6R Polyclonal Antibody at dilution of 1:200
Product Name
IL6R Polyclonal Antibody
Catalog Number
RD240344A
Clonality
Polyclonal
Purification Method
Antigen Affinity Purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.
Immunogen Information
Immunogen
Recombinant Human Interleukin-6 receptor subunit alpha protein
Swissprot
P08887
Synonyms
CD 126CD126CD126 antigengp80IL 6R 1IL 6R alphaIL 6RIL-6 receptor alpha chainIL-6 receptor subunit alphaIL-6R 1IL-6R subunit alphaIL-6R-alphaIL-6RAIL6QIl6rIL6RAIL6RAIL6RQInterleukin 6 receptorinterleukin 6 receptoralphaInterleukin-6 re
Calculated MW
40,51 kDa
Observed MW
80 kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC
Conjugation
Unconjugated
Dilution
WB 1:1000-1:2000 IHC 1:100-1:300
Concentration
1 mg/mL
Storage Buffer
PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas