IL6ST Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD90232A
Western blot analysis of extracts of various cell lines using IL6ST Polyclonal Antibody at 1:1000 dilution.
Immunofluorescence analysis of U2OS cells using IL6ST Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
Immunofluorescence analysis of NIH/3T3 cells using IL6ST Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
Immunofluorescence analysis of C6 cells using IL6ST Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
Product Name
IL6ST Polyclonal Antibody
Catalog Number
RD90232A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants have been described. A related pseudogene has been identified on chromosome 17.
Immunogen Information
Immunogen
Recombinant fusion protein of human IL6ST
Gene ID
3572
Swissprot
P40189
Synonyms
IL6STCD130CDW130GP130IL-6RB
Calculated MW
16kDa
Observed MW
16KDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IF
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000,IF 1:50-1:200
Concentration
1mg/mL
Storage Buffer
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.