IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus. IL-8(6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8(5-77) has increased activity on neutrophil activation and IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8(1-77), respectively.
Immunogen Information
Immunogen
Synthesized peptide derived from the C-terminal region of human IL8.
Swissprot
P10145
Synonyms
(Ala-IL-8)77(Ser-IL-8)729E3Beta thromboglobulin like proteinC-X-C motif chemokine 8CEF-4chemokineCXC motifligand 8CXCL8EmoctakinGCP-1GCP/IL-8 protein IGCP/IL-8 protein IIGCP/IL-8 protein IIIGCP/IL-8 protein IVGCP/IL-8 protein VGCP/IL-8 pr
Calculated MW
11 kDa
Observed MW
11 kDa
Applications
Reactivity
Human
Tested Applications
WB,IHC-p,IF,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:100-1:300, IF 1:100-1:300, ELISA 1:20000
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol pH 7.4.