This gene encodes a protein with a kinase-like domain and four ankyrin-like repeats. The encoded protein associates at the cell membrane with the cytoplasmic domain of beta integrins, where it regulates integrin-mediated signal transduction. Activity of this protein is important in the epithelial to mesenchymal transition, and over-expression of this gene is implicated in tumor growth and metastasis. Alternative splicing results in multiple transcript variants.
Immunogen Information
Immunogen
Recombinant protein of human ILK
Swissprot
Q13418
Synonyms
59 kDa serine/threonine protein kinase59 kDa serine/threonine-protein kinaseDKFZp686F1765Epididymis secretory protein Li 28HEL S 28ILK 1ILK 2ILKILK-1ILK-2ILKILK1ILK2Integrin linked kinase 2Integrin linked KinaseIntegrin linked protein kinas
Calculated MW
51 kDa
Gene Accession
BC001554
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:50-1:200
Concentration
0.3 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4