IMPDH2 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD266509A
Western blot analysis of extracts of various cell lines using IMPDH2 Polyclonal Antibody at dilution of 1:1000.
Product Name
IMPDH2 Polyclonal Antibody
Catalog Number
RD266509A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation.
Immunogen Information
Immunogen
Recombinant fusion protein of human IMPDH2 (NP_000875.2).
Gene ID
3615
Swissprot
P12268
Synonyms
IMPDH2IMPD2IMPDH-II
Calculated MW
55 kDa
Observed MW
56 kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas