IMPDH2 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD75914A
Western Blot analysis of A549 cell using IMPDH2 Polyclonal Antibody at dilution of 1:650
Immunohistochemistry of paraffin-embedded Human lung cancer using IMPDH2 Polyclonal Antibody at dilution of 1:60
Immunohistochemistry of paraffin-embedded Human liver cancer using IMPDH2 Polyclonal Antibody at dilution of 1:60
Product Name
IMPDH2 Polyclonal Antibody
Catalog Number
RD75914A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation.
Immunogen Information
Immunogen
Recombinant protein of human IMPDH2
Swissprot
P12268
Synonyms
IMDH2IMP (inosine monophosphate) dehydrogenase 2IMP dehydrogenase 2IMP oxireductase 2IMPD 2IMPD2IMPDH 2IMPDH IIIMPDH-IIImpdh2Inosine 5' monophosphate dehydrogenase 2Inosine 5' phosphate dehydrogenase 2Inosine monophosphate dehydrogenase type I
Calculated MW
56 kDa
Gene Accession
BC006124
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:50-1:200
Concentration
0.5 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas