IP3R Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD90308A
Western blot analysis of extracts of Mouse brain using IP3R Polyclonal Antibody at 1:1000 dilution.
Western blot analysis of extracts of various cell lines using IP3R Polyclonal Antibody at 1:1000 dilution.
Immunofluorescence analysis of U2OS cells using IP3R Polyclonal Antibody at dilution of 1:100. Perform microwave antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IF staining protocol. Blue: DAPI for nuclear staining.
Product Name
IP3R Polyclonal Antibody
Catalog Number
RD90308A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes an intracellular receptor for inositol 1,4,5-trisphosphate. Upon stimulation by inositol 1,4,5-trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in this gene cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for this gene.
Immunogen Information
Immunogen
A synthetic peptide of human IP3R
Gene ID
3708
Swissprot
Q14643
Synonyms
ITPR1ACVCLA4INSP3R1IP3RIP3R1PPP1R94SCA15SCA16SCA29inositol 145-trisphosphate receptor type 1
Calculated MW
198kDa
Observed MW
Refer to figures
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IF
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000,IF 1:50-1:200
Concentration
1mg/mL
Storage Buffer
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Research Areas