This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines.
Immunogen Information
Immunogen
Synthetic peptide of human IQGAP1
Swissprot
P46940
Synonyms
HUMORFA01IQ motif containing GTPase activating protein 1IQGA1Iqgap1KIAA0051p195Ras GTPase activating like protein 1Ras GTPase-activating-like protein IQGAP1RasGAP-like with IQ motifsSAR1