IQSEC1 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD88664A
Western blot analysis of extracts of various cell lines using IQSEC1 Polyclonal Antibody at 1:1000 dilution.
Product Name
IQSEC1 Polyclonal Antibody
Catalog Number
RD88664A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Guanine nucleotide exchange factor for ARF1 and ARF6. Guanine nucleotide exchange factor activity is enhanced by lipid binding. Accelerates GTP binding by ARFs of all three classes. Guanine nucleotide exchange protein for ARF6, mediating internalization of beta-1 integrin. Involved in neuronal development (Probable. In neurons, plays a role in the control of vesicle formation by endocytoc cargo. Upon long term depression, interacts with GRIA2 and mediates the activation of ARF6 to internalize synaptic AMPAR receptors (By similarity.
Immunogen Information
Immunogen
Recombinant fusion protein of human IQSEC1
Gene ID
9922
Swissprot
Q6DN90
Synonyms
IQSEC1ARF-GEP100ARFGEP100BRAG2GEP100
Calculated MW
65kDa
Observed MW
55kDa
Applications
Reactivity
Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:1000
Concentration
1mg/mL
Storage Buffer
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.