IRF4 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD76907A
Western Blot analysis of Jurkat cell using IRF4 Polyclonal Antibody at dilution of 1:400
Product Name
IRF4 Polyclonal Antibody
Catalog Number
RD76907A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene.
Immunogen Information
Immunogen
Synthetic peptide of human IRF4
Swissprot
Q15306
Synonyms
Interferon regulatory factor 4IRF 4IRF-4Irf4IRF4LSIRFLymphocyte specific interferon regulatory factorLymphocyte specific IRFLymphocyte-specific interferon regulatory factorMultiple myeloma oncogene 1MUM 1MUM1NF EM5NF-EM5NFEM5PU.1 interactio
Calculated MW
52 kDa
Gene Accession
NP_002451
Applications
Reactivity
Human,Mouse
Tested Applications
WB,ELISA
Conjugation
Unconjugated
Dilution
WB 1:200-1:1000
Concentration
0.2 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas