IRF9 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD89379A
Western blot analysis of extracts of various cell lines using IRF9 Polyclonal Antibody at 1:1000 dilution.
Product Name
IRF9 Polyclonal Antibody
Catalog Number
RD89379A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Transcription factor that plays an essential role in anti-viral immunity. It mediates signaling by type I IFNs (IFN-alpha and IFN-beta. Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1 are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. IRF9/ISGF3G associates with the phosphorylated STAT1:STAT2 dimer to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.
Immunogen Information
Immunogen
Recombinant fusion protein of human IRF9
Gene ID
10379
Swissprot
Q00978
Synonyms
IRF9IRF-9ISGF3ISGF3Gp48interferon regulatory factor 9
Calculated MW
33kDa/35kDa/42kDa
Observed MW
48KDa
Applications
Reactivity
Human
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1mg/mL
Storage Buffer
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Research Areas