This gene encodes a protein with MIT-interacting motifs that interacts with components of endosomal sorting complexes required for transport (ESCRT). ESCRT functions in vesicle budding, such as that which occurs during membrane abscission in cytokinesis. There is a pseudogene for this gene on chromosome 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Immunogen Information
Immunogen
Synthetic peptide of human IST1
Swissprot
P53990
Synonyms
hIST1Increased sodium tolerance 1Increased sodium tolerance 1 homologIST1 homologIST1KIAA0174MAPK activating protein PM28MGC117220MGC128433Putative MAPK-activating protein PM28