ITGA2B Monoclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD85510A
Immunohistochemistry of paraffin-embedded Human breast cancer tissue using ITGA2B Monoclonal Antibody at dilution of 1:200.
Product Name
ITGA2B Monoclonal Antibody
Catalog Number
RD85510A
Clonality
Monoclonal
Purification Method
Protein A purification
Isotype
IgG
Host
Mouse
Background
ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.
Immunogen Information
Immunogen
Synthetic Peptide
Swissprot
P08514
Synonyms
antigen CD41BDPLT16BDPLT2CD41CD41Bform 2GP2BGPalpha IIbGPIIbGTGTAHPA3Integrin alpha 2bIntegrin alpha IIbIntegrin alpha-IIb light chainIntegrinalpha 2b (platelet glycoprotein IIb of IIb/IIIa complexantigen CD41)ITA2BItga2bITGABplatelet
Applications
Reactivity
Human
Tested Applications
IHC-p
Conjugation
Unconjugated
Dilution
IHC 1:50-200
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas