ITGA2B Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD78189A
Western Blot analysis of Human placenta and fetal liver tissue using ITGA2B Polyclonal Antibody at dilution of 1:650
Product Name
ITGA2B Polyclonal Antibody
Catalog Number
RD78189A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.
Immunogen Information
Immunogen
Recombinant protein of human ITGA2B
Swissprot
P08514
Synonyms
antigen CD41BDPLT16BDPLT2CD41CD41Bform 2GP2BGPalpha IIbGPIIbGTGTAHPA3Integrin alpha 2bIntegrin alpha IIbIntegrin alpha-IIb light chainIntegrinalpha 2b (platelet glycoprotein IIb of IIb/IIIa complexantigen CD41)ITA2BItga2bITGABplatelet
Calculated MW
113 kDa
Gene Accession
BC117443
Applications
Reactivity
Human,Mouse
Tested Applications
WB,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
0.5 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas