ITGA3 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD218119A
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using ITGA3 Polyclonal Antibody at dilution of 1:45(×200)
Immunohistochemistry of paraffin-embedded Human tonsil tissue using ITGA3 Polyclonal Antibody at dilution of 1:45(×200)
Product Name
ITGA3 Polyclonal Antibody
Catalog Number
RD218119A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
ITGA3,also named as MSK18,CD49c,GAPB3 and FRP-2,belongs to the integrin alpha chain family. It is a receptor for fibronectin,laminin,collagen,epiligrin,thrombospondin and CSPG4. ITGA3 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration. ITGA3 is highly concentrated in epithelial cells where it strongly adheres to Laminin-5 and Laminin-5 induced rapid adhesion can be blocked by antibodies against the alpha-3 integrin subunit. It can be cleaved into heavy chain(840aa) and light chain(176aa). This antibody can recognize the heavy chain.
Immunogen Information
Immunogen
Synthetic peptide of human ITGA3
Swissprot
P26006
Synonyms
AA407068Antigen identified by monoclonal J143CD49 antigen like family member CCD49 antigen-like family member CCD49cCD49c antigenFLJ34631FLJ34704FRP 2FRP-2FRP2Galactoprotein B3GAP B3GAPB3Integrin alpha 3Integrin alpha-3 light chainIntegrin
Gene Accession
NP002195
Applications
Reactivity
Human, Mouse
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:40-1:200, ELISA 1:5000-1:10000
Concentration
1.32 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas