ITGAE Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD78190A
Immunohistochemistry of paraffin-embedded Human colon cancer tissue using ITGAE Polyclonal Antibody at dilution of 1:60
Immunohistochemistry of paraffin-embedded Human lung cancer using ITGAE Polyclonal Antibody at dilution of 1:60
Product Name
ITGAE Polyclonal Antibody
Catalog Number
RD78190A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination with the beta 7 integrin, this protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen. This protein is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL), and in addition to a role in adhesion, it may serve as an accessory molecule for IEL activation.
Immunogen Information
Immunogen
Recombinant protein of human ITGAE
Swissprot
P38570
Synonyms
A530055J10alpha-E1alpha-M290aM290Antigen CD103CD 103CD103CD103 antigenHML 1 antigenHML-1 antigenHML1 antigenHuman mucosal lymphocyte antigen 1Human mucosal lymphocyte antigen 1alpha subunitHuminaeIntegrin alpha E heavy chainIntegrin alpha
Gene Accession
BC113436
Applications
Reactivity
Human
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.5 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas