ITGB3BP Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD266360A
Immunohistochemistry of paraffin-embedded Human liver using ITGB3BP Polyclonal Antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded Human appendix using ITGB3BP Polyclonal Antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded Human gastric cancer using ITGB3BP Polyclonal Antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded Mouse brain using ITGB3BP Polyclonal Antibody at dilution of 1:100 (40x lens).
Product Name
ITGB3BP Polyclonal Antibody
Catalog Number
RD266360A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor of NF-kappaB-dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants.
Immunogen Information
Immunogen
Recombinant fusion protein of human ITGB3BP (NP_055103.3).
Gene ID
23421
Swissprot
Q13352
Synonyms
ITGB3BPCENP-RCENPRHSU37139NRIF3TAP20
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas