ITGB3BP Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD75228A
Immunohistochemistry of paraffin-embedded Human gasrtic cancer tissue using ITGB3BP Polyclonal Antibody at dilution 1:50
Immunohistochemistry of paraffin-embedded Human brain tissue using ITGB3BP Polyclonal Antibody at dilution 1:50
Variation
Quantity
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Overview
Product Name
ITGB3BP Polyclonal Antibody
Catalog Number
RD75228A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor of NF-kappaB-dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants.
Immunogen Information
Immunogen
Recombinant protein of human ITGB3BP
Swissprot
Q13352
Synonyms
Beta 3 endonexinBeta3 endonexinBeta3 endonexin long formCENP RCENPRCENPRCentromere protein RendonexinBeta-3HSU37139Integrin beta 3 binding protein (beta3-endonexin)Integrin beta 3 binding proteinNRIF 3NRIF3Nuclear receptor interacting factor
Gene Accession
BC014385
Applications
Reactivity
Human
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.7 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas