This gene encodes an intracellular receptor for inositol 1,4,5-trisphosphate. Upon stimulation by inositol 1,4,5-trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in this gene cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for this gene.
Immunogen Information
Immunogen
Synthetic peptide of human ITPR1
Swissprot
Q14643
Synonyms
45-trisphosphate receptor5-trisphosphate receptor type 1DKFZp313E1334DKFZp313N1434inositol 1 4 5 triphosphate receptor type 1Inositol 1 4 5 trisphosphate Receptor Type 1Inositol 1InsP3R1IP3IP3 receptorIP3 receptor isoform 1IP3R 1IP3RIP3R1IT
Gene Accession
NP_001093422
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.8 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4