JAG1 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD79102A
Immunohistochemistry of paraffin-embedded Human brain tissue using JAG1 Polyclonal Antibody at dilution 1:40
Immunohistochemistry of paraffin-embedded Human colon cancer tissue using JAG1 Polyclonal Antibody at dilution 1:40
Product Name
JAG1 Polyclonal Antibody
Catalog Number
RD79102A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.
Immunogen Information
Immunogen
Synthetic peptide of human JAG1
Swissprot
P78504
Synonyms
AGSAHDAWSCD 339CD339CD339 antigenHeadturnerhJ1HtuJag 1Jag1JAG1Jagged 1Jagged1 (Alagille syndrome)Jagged1JAGL1MGC104644OTTHUMP00000030278Protein jagged-1Ser 1Ser1Serrate 1Slalom
Gene Accession
NP_000205
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.9 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas