This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.
Immunogen Information
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse JAK2
Swissprot
Q62120,Q62689
Synonyms
JAK 2JAK-2JAK2JAK2Janus Activating Kinase 2Janus kinase 2 (a protein tyrosine kinase)Janus kinase 2JTK 10JTK10kinase Jak2OTTHUMP00000043260THCYT3Tyrosine protein kinase JAK2Tyrosine-protein kinase JAK2
Calculated MW
130 kDa
Observed MW
130 kDa
Applications
Reactivity
Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4