This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.
Immunogen Information
Immunogen
Synthetic peptide of human JAK2
Swissprot
O60674
Synonyms
JAK 2JAK-2JAK2JAK2Janus Activating Kinase 2Janus kinase 2 (a protein tyrosine kinase)Janus kinase 2JTK 10JTK10kinase Jak2OTTHUMP00000043260THCYT3Tyrosine protein kinase JAK2Tyrosine-protein kinase JAK2
Gene Accession
NP_004963
Applications
Reactivity
Human,Rat
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.3 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4