KBTBD8 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD89114A
Western blot analysis of extracts of Rat lung using KBTBD8 Polyclonal Antibody at 1:1000 dilution.
Product Name
KBTBD8 Polyclonal Antibody
Catalog Number
RD89114A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1 E3 ubiquitin ligase complex that acts as a regulator of neural crest specification. The BCR(KBTBD8 complex acts by mediating monoubiquitination of NOLC1 and TCOF1: monoubiquitination promotes the formation of a NOLC1-TCOF1 complex that acts as a platform to connect RNA polymerase I with enzymes responsible for ribosomal processing and modification, leading to remodel the translational program of differentiating cells in favor of neural crest specification.
Immunogen Information
Immunogen
Recombinant fusion protein of human KBTBD8
Gene ID
84541
Swissprot
Q8NFY9
Synonyms
TA-KRPTAKRPKBTBD8
Observed MW
45kDa
Applications
Reactivity
Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1mg/mL
Storage Buffer
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.