Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and may be involved in the regulation of insulin secretion by glucose. It associates with two other G-protein-activated potassium channels to form a heteromultimeric pore-forming complex.
Immunogen Information
Immunogen
Synthetic peptide of human KCNJ6
Swissprot
P48051
Synonyms
inwardly rectifying subfamily J member 6BIR1G protein activated inward rectifier potassium channel 2G protein-activated inward rectifier potassium channel 2GIRK-2GIRK2hiGIRK2Inward rectifier K(+) channel Kir3.2Inward rectifier potassium channel KI
Calculated MW
48 kDa
Gene Accession
NP_002231
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:50-1:200
Concentration
0.9 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4