MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smootHuman, Mouseuscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit whicHuman, Mouseay partially inactivate or slightly decrease the activation time of MaxiK alpha subunit currents. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 22.
Immunogen Information
Immunogen
Synthetic peptide of human KCNMB3
Swissprot
Q9NPA1
Synonyms
BK channel subunit beta 3BK channel subunit beta-3BKbeta 3BKbeta3Calcium activated potassium channel beta 3 subunitCalcium activated potassium channel subfamily M subunit beta 3Calcium activated potassium channel subunit beta 3Calcium-activated pot
Calculated MW
32 kDa
Gene Accession
NP_055222
Applications
Reactivity
Human,Mouse
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:25-1:100
Concentration
0.5 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4