The protein encoded by this gene is part of a potentially heterotetrameric voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization, which promotes calcium influx. The encoded protein may be part of the predominant calcium-activated potassium channel in T-lymphocytes. This gene is similar to other KCNN family potassium channel genes, but it differs enough to possibly be considered as part of a new subfamily.
Immunogen Information
Immunogen
Synthetic peptide of human KCNN4
Swissprot
O15554
Synonyms
DHS2hIKCa1hKCa4hSK4IKIK1IKCa1Intermediate conductance calcium activated potassium channel protein 4Intermediate conductance calcium-activated potassium channel protein 4KCa3.1KCa4KCNN 4Kcnn4KCNN4Potassium calcium activated channel subfamily
Gene Accession
NP_002241
Applications
Reactivity
Human
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:100-1:300
Concentration
1.5 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4