This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein containing a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two PHD-type zinc fingers. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form, and as a transcriptional repressor.
Immunogen Information
Immunogen
Synthetic peptide of human KDM4A
Swissprot
O75164
Synonyms
JHDM3AJmjC domain containing histone demethylation protein 3AJmjC domain-containing histone demethylation protein 3AJMJD2JMJD2Ajumonji C domain containing histone demethylase 3AJumonji domain containing 2Jumonji domain containing 2AJumonji domain
Calculated MW
121 kDa
Gene Accession
NP_055478
Applications
Reactivity
Human,Mouse
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:50-1:200
Concentration
0.7 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4