KDM4C Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD76915A
Western Blot analysis of Mouse heart and brain tissue using KDM4C Polyclonal Antibody at dilution of 1:800
Product Name
KDM4C Polyclonal Antibody
Catalog Number
RD76915A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma. Alternative splicing results in multiple transcript variants.
Immunogen Information
Immunogen
Synthetic peptide of human KDM4C
Swissprot
Q9H3R0
Synonyms
bA146B14.1GASC 1 proteinGASC-1 proteinGASC1Gene amplified in squamous cell carcinoma 1 proteinJHDM3CJmjC domain containing histone demethylation protein 3CJmjC domain-containing histone demethylation protein 3CJMJD2CJumonji domain containing 2CJ
Calculated MW
120 kDa
Gene Accession
NP_055876
Applications
Reactivity
Human,Mouse
Tested Applications
WB,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas