KDM5B Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD76924A
Immunohistochemistry of paraffin-embedded Human colon cancer tissue using KDM5B Polyclonal Antibody at dilution 1:40
Product Name
KDM5B Polyclonal Antibody
Catalog Number
RD76924A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
PLU-1 is a large (1,544 amino acid) nuclear protein that interacts with brain factor-1 (BF-1) and paired box 9 (PAX9), both of which are developmental transcription factors. PLU-1 belongs to the testis-cancer antigen group of proteins and is a member of the ARID family of DNA binding proteins. It is a multi-domain protein with strong transcriptional repression properties. PLU-1 shows restricted expression in adult tissues, with high expression in testis and transient expression in the pregnant mammary gland. Both the PLU-1 gene and the PLU-1 protein product are specifically upregulated in breast cancer. PLU-1 may be important in meiotic transcription because of its apparent association with chromatin.
Immunogen Information
Immunogen
Synthetic peptide of human KDM5B
Swissprot
Q9UGL1
Synonyms
Cancer/testis antigen 31CT31Histone demethylase JARID1BJARID1BJumonji AT rich interactive domain 1BJumonji/ARID domain-containing protein 1BKdm5bKDM5BLysine (K) specific demethylase 5BLysine demethylase 5BLysine specific demethylase 5BLysine-sp
Gene Accession
NP_006609
Applications
Reactivity
Human,Mouse
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
1.5 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas