Protein CIP2Aalso known ascancerous inhibitor of PP2A(CIP2A) is aproteinthat in humans is encoded by theKIAA1524gene. Protein phosphatase 2A (PP2A) is a cellular tumor suppressor which inhibits cell proliferation and transformation of normal cells to malignant cancer cells. Inhibition of PP2A activity is a prerequisite for human cell transformation. However, the in vivo mechanisms by which PP2A activity is inhibited in spontaneously transformed human cancer cells have been unclear.
Immunogen Information
Immunogen
Recombinant protein of human KIAA1524
Swissprot
Q8TCG1
Synonyms
Cancerous inhibitor of PP2ACancerous Inhibitor of Protein Phosphatase 2ACIP2ACIP2AFLJ12850Kiaa1524MGC163436p90p90 autoantigenProtein CIP2A
Calculated MW
102 kDa
Gene Accession
BC130564
Applications
Reactivity
Human,Mouse
Tested Applications
WB,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
0.5 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4