KIF1C Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD75934A
Immunohistochemistry of paraffin-embedded Human placenta tissue using KIF1C Polyclonal Antibody at dilution 1:60
Immunohistochemistry of paraffin-embedded Human placenta tissue using KIF1C Polyclonal Antibody at dilution 1:60
Immunohistochemistry of paraffin-embedded Human sarcoma tissue using KIF1C Polyclonal Antibody at dilution 1:60
Immunohistochemistry of paraffin-embedded Human sarcoma tissue using KIF1C Polyclonal Antibody at dilution 1:60
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Overview

Circle
Product Name
KIF1C Polyclonal Antibody
Catalog Number
RD75934A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit

Background

Circle
The kinesins constitute a large family of microtubule-dependent motor proteins, which are responsible for the distribution of numerous organelles, vesicles and macromolecular complexes throughout the cell . Individual kinesin members play crucial roles in cell division, intracellular transport, and membrane trafficking events including endocytosis and transcytosis . KIF1C is a member of the KIF1/Unc104 family of kinesin-like proteins, which are involved in the transport of mitochondria or synaptic vesicles in axons . Human KIF1C maps to chromosome 17p13 and encodes a predicted 1,103 amino acid protein with abundant expression in heart and skeletal muscle . Tyrosine phosphorylation is a putative regulator of KIF1C mediated retrograde transport of Golgi vesicles to the endoplasmic reticulum. KIF1C is capable of forming homodimers and can noncovalently associate with 14-3-3 beta, gamma, epsilon and zeta . In mouse macrophages, KIF1C is required for anthrax lethal toxin resistance.

Immunogen Information

Circle
Immunogen
Recombinant protein of human KIF1C
Swissprot
O43896
Synonyms
Kif1cKIF1CKinesin family member 1CKinesin-like protein KIF1CLTXS1
Gene Accession
BC034993

Applications

Circle
Reactivity
Human,Mouse,Rat
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.6 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

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