KIF3A Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD77485A
Western Blot analysis of Mouse brain and Human brain malignant glioma tissue using KIF3A Polyclonal Antibody at dilution of 1:750
Western Blot analysis of Mouse brain and Human brain malignant glioma tissue using KIF3A Polyclonal Antibody at dilution of 1:750
Immunohistochemistry of paraffin-embedded Human thyroid cancer using KIF3A Polyclonal Antibody at dilution of 1:40
Immunohistochemistry of paraffin-embedded Human thyroid cancer using KIF3A Polyclonal Antibody at dilution of 1:40
Immunohistochemistry of paraffin-embedded Human lung cancer using KIF3A Polyclonal Antibody at dilution of 1:40
Immunohistochemistry of paraffin-embedded Human lung cancer using KIF3A Polyclonal Antibody at dilution of 1:40
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Overview

Circle
Product Name
KIF3A Polyclonal Antibody
Catalog Number
RD77485A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit

Background

Circle
Kinesin-like protein KIF3Ais aproteinthat in humans is encoded by theKIF3Agene. Members of the heterotrimeric kinesin II family of microtubule associated motors generally contain two different motor subunits from the KIF3 family, which includes KIF3A, B and C. KIF3 isoforms mediate anterograde transport of membrane bound organelles in neurons and melanosomes, transport between the endoplasmic reticulum and the Golgi, and transport of protein complexes within cilia and flagella required for their morphogenesis. KIF3A may influence neurogenesis at the level of embryonic cellular events, where the asymmetry of the genetic control circuit controlling left-right (L-R) axis determination is defined. Loss of KIF3A function in mice photoreceptors causes apoptotic cell death, suggesting that kinesin II mediated transport is required for proper cell fate.

Immunogen Information

Circle
Immunogen
Recombinant protein of human KIF3A
Swissprot
Q9Y496
Synonyms
KIF 3KIF 3AKIF3Kif3aKIF3AKiflKinesin family member 3AKinesin family protein 3Kinesin family protein 3AKinesin like protein KIF 3AKinesin like protein KIF3AKinesin-like protein KIF3AKns3Microtubule plus end directed kinesin motor 3AMicrotubul
Calculated MW
80 kDa
Gene Accession
BC045542

Applications

Circle
Reactivity
Human,Mouse
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:50-1:200
Concentration
0.2 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

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